Cancer Isn't Going Undetected By Chance — It's Undetected By Design
Liver cancer has no reliable early-warning signs. Most patients feel fine until the disease is already advanced. The tools to screen for it have been inaccessible, invasive, or simply absent — until now.
3%
5-year survival rate when liver cancer is caught at Stage IV. The disease is nearly always fatal at this point.
34%
5-year survival rate when caught at Stage I or II — over 11× higher. Early detection is the difference between life and death.
2 in 3
high-risk Americans — those with cirrhosis, hepatitis B/C, or fatty liver disease — are not on any regular liver cancer screening program. (Source: ACS / SEER 2023)
The Inconvenient Truth About Liver Cancer
Liver cancer (HCC) is one of the fastest-growing cancers in the United States. Yet most at-risk patients receive no routine surveillance. Why? Because existing screening methods are expensive, require hospital imaging, and demand repeat visits that patients — especially older adults — simply don’t complete.
“Most patients who die from liver cancer had a cancer that, if found six months earlier, could have been treated. The barrier isn’t biology — it’s access to detection.”
The result: 75% of American liver cancer patients are diagnosed when curative treatment is no longer possible. This isn’t inevitable. It’s a gap we were built to close.
FUSING SCIENCE WITH EARLY DETECTION
Most Liver Cancers Are Found Too Late. We Change That.
MoleculeDx’s simple blood test detects hepatocellular carcinoma (HCC) at Stage I & II — when it’s most treatable. No hospital visit. No biopsy. Results in 24 hours.
of liver cancers are detected at late stage — when survival drops from 34% to just 3%
41K+
new HCC cases diagnosed in the US every year — and rising
700K+
high-risk Americans with no current screening protocol in place
UPMC Partnership: Walk-in testing now available at University of Pittsburgh Medical Center locations
Why MoleculeDx
No Biopsy. No Imaging. No Barriers.
Traditional liver cancer diagnosis involves invasive procedures with real risks. Our blood-based test is different — simple, safe, and accessible from home.
From booking to results, our entire process is designed for simplicity — especially for patients who find hospital visits difficult.
1
Book Online
Schedule your at-home blood draw in minutes at booking.moleculedx.com. Pick a time that works for you.
2
Phlebotomist Comes to You
A certified partner (Portamedic or Travalab) visits your home and collects a standard blood sample — usually under 10 minutes.
3
AI-Powered Analysis
Our Fusion-detect™ platform screens your sample for liver cancer fusion gene biomarkers with industry-leading accuracy.
4
Results in 24 Hours
Receive your certified report digitally. If further follow-up is needed, we connect you with a specialist immediately.
At Your Front Door
Certified phlebotomist within 48 hrs
At-Home Collection
Your Home Is Your Clinic
We’ve eliminated every barrier between you and early cancer detection. No hospital appointments. No waiting rooms. No travel. A trained professional comes directly to you.
Book in 2 Minutes Online
Choose your date and 2-hour arrival window at booking.moleculedx.com — available 7 days a week, including evenings.
Certified Phlebotomist Visits You
Our partners Portamedic and Travalab send nationally-certified phlebotomists to your door. The draw takes under 10 minutes.
Temperature-Controlled Transport
Your sample is sealed and transported via cold-chain courier to our CLIA lab — maintaining integrity for the most accurate results.
Results Delivered to Your Phone
A secure digital report lands in your inbox within 24 hours. No chasing down results — everything is clear and explained.
Our Technology
Powered by Fusion-detect™ AI
Fusion-detect™ is our proprietary genomic sequencing and AI analysis platform. It detects chromosomal fusion events — a hallmark of early-stage HCC — that are completely missed by conventional blood markers like AFP.
The platform has gone through four major AI training generations, each time dramatically improving detection accuracy. Here’s how AI transformed liver cancer detection:
2018 — Foundation
Fusion Gene Discovery
Researchers identified 14 HCC-specific fusion gene events in circulating tumor DNA that appear up to 18 months before imaging-detectable tumors.
2020 — Breakthrough
Fusion Gene Discovery
Initial ML classifier trained on 8,000 samples. Already outperformed AFP testing — but we knew we could go further.
2022 — Scale
Deep Learning on 50K Samples: 92.1%
A transformer-based neural network trained on 50,000+ annotated patient samples across 12 ethnic backgrounds for bias-free results.
2024 — Present
Fusion-detect™ v4: 96.7% Accuracy
Real-time ensemble AI with multi-biomarker fusion scoring, continuous learning pipeline, and <3% false positive rate. CLIA-certified and peer-review validated.
✦ 96.7% accuracy confirmed across 3 independent clinical validation cohorts. Results submitted for peer-reviewed publication.
The Growing Crisis
Liver Cancer Cases Are Rising Every Year
WHO and SEER data confirm liver cancer (HCC) is one of the world’s fastest-growing cancers. Without early detection tools, this trend means more late-stage diagnoses and preventable deaths.
Global & US Liver Cancer (HCC) Incidence — 2015 to 2023
Source: WHO Global Cancer Observatory (GLOBOCAN), NCI SEER Program 2023
Global Cases (×1,000)
US Cases (×1,000)
The trajectory is clear: liver cancer is rising steadily. Early detection via blood-based screening is the only scalable intervention that can reverse the mortality curve without requiring massive infrastructure investment.
Global liver cancer incidence has risen 75% over the past 20 years. We break down the WHO GLOBOCAN numbers — and what they mean for high-risk patients in the US right now.
If you have hepatitis, cirrhosis, or NAFLD, your doctor may be relying on ultrasound and AFP — tools that miss over 40% of early-stage HCC. Here’s what the evidence shows.
Machine learning models trained on fusion gene biomarkers are outperforming 40 years of conventional AFP testing — and changing what’s possible in oncology screening.
Our Partners
A Trusted Network Behind Every Test
We’ve partnered with the best in US phlebotomy, clinical medicine, and health insurance to make testing seamless from booking to results.
P
Portamedic
One of America’s largest mobile health services networks — certified phlebotomists serving all 50 states, available 7 days a week for at-home blood draws.
Travalab’s mobile laboratory specialists provide concierge-level phlebotomy services, ensuring the highest sample quality and patient comfort from first contact.
Not sure if you’re covered? Our patient support team will verify your insurance coverage for free before you book. Call us or check online at booking.moleculedx.com.
Exclusive Partnership
Testing Available at Every UPMC Location
Through our exclusive partnership with University of Pittsburgh Medical Center, you can walk into any UPMC facility today — no prior appointment required for testing referral.