The Earlier We Find It, The Better We Fight It.

A simple blood test detects hepatocellular carcinoma at Stage I & II — when survival rates are 11× higher. No hospital visit. Results in 24 hours.

MoleculeDx at a Glance — Updated in real time

Live Data Feed

Tests Completed

48,671

Patients screened since launch

+688 today

Accuracy Rate

96.7%

Fusion-detect™ clinical validation

↑ vs 52% AFP standard

Late-Stage Detection (US)

75%

Of HCC cases found when survival is just 3%

↓ We’re changing this

Turnaround Time

24hrs

From blood draw to certified digital result

↑ vs 7–14 day imaging

The Problem

Cancer Isn't Going Undetected By Chance — It's Undetected By Design

Liver cancer has no reliable early-warning signs. Most patients feel fine until the disease is already advanced. The tools to screen for it have been inaccessible, invasive, or simply absent — until now.

3%

5-year survival rate when liver cancer is caught at Stage IV. The disease is nearly always fatal at this point.

34%

5-year survival rate when caught at Stage I or II — over 11× higher. Early detection is the difference between life and death.

2 in 3

high-risk Americans — those with cirrhosis, hepatitis B/C, or fatty liver disease — are not on any regular liver cancer screening program. (Source: ACS / SEER 2023)

The Inconvenient Truth About Liver Cancer

Liver cancer (HCC) is one of the fastest-growing cancers in the United States. Yet most at-risk patients receive no routine surveillance. Why? Because existing screening methods are expensive, require hospital imaging, and demand repeat visits that patients — especially older adults — simply don’t complete.

“Most patients who die from liver cancer had a cancer that, if found six months earlier, could have been treated. The barrier isn’t biology — it’s access to detection.”

The result: 75% of American liver cancer patients are diagnosed when curative treatment is no longer possible. This isn’t inevitable. It’s a gap we were built to close.

FUSING SCIENCE WITH EARLY DETECTION

Most Liver Cancers Are Found Too Late. We Change That.

MoleculeDx’s simple blood test detects hepatocellular carcinoma (HCC) at Stage I & II — when it’s most treatable. No hospital visit. No biopsy. Results in 24 hours.

The Liver Cancer Crisis in America

75%

of liver cancers are detected at late stage — when survival drops from 34% to just 3%

41K+

new HCC cases diagnosed in the US every year — and rising
 

700K+

high-risk Americans with no current screening protocol in place
 

UPMC Partnership: Walk-in testing now available at University of Pittsburgh Medical Center locations

Why MoleculeDx

No Biopsy. No Imaging. No Barriers.

Traditional liver cancer diagnosis involves invasive procedures with real risks. Our blood-based test is different — simple, safe, and accessible from home.

Traditional Methods

MoleculeDx Fusion-detect™

96.7%

Accuracy

Industry-Leading Precision

Fusion-detect™ outperforms every conventional liver cancer screening method currently available in the US.

Clinical Performance

How We Compare

Side-by-side accuracy metrics against the standard tests used in current clinical practice.

Fusion-detect™ — Overall Accuracy

96.7%

Fusion-detect™ — Sensitivity

94.2%

Fusion-detect™ — Specificity

98.1%

Standard AFP Test (industry avg)

~52%

The Process

Four Simple Steps to Peace of Mind

From booking to results, our entire process is designed for simplicity — especially for patients who find hospital visits difficult.

1

Book Online

Schedule your at-home blood draw in minutes at booking.moleculedx.com. Pick a time that works for you.

2

Phlebotomist Comes to You

A certified partner (Portamedic or Travalab) visits your home and collects a standard blood sample — usually under 10 minutes.

3

AI-Powered Analysis

Our Fusion-detect™ platform screens your sample for liver cancer fusion gene biomarkers with industry-leading accuracy.

4

Results in 24 Hours

Receive your certified report digitally. If further follow-up is needed, we connect you with a specialist immediately.

At Your Front Door

Certified phlebotomist within 48 hrs

At-Home Collection

Your Home Is Your Clinic

We’ve eliminated every barrier between you and early cancer detection. No hospital appointments. No waiting rooms. No travel. A trained professional comes directly to you.

Book in 2 Minutes Online

Choose your date and 2-hour arrival window at booking.moleculedx.com — available 7 days a week, including evenings.

Certified Phlebotomist Visits You

Our partners Portamedic and Travalab send nationally-certified phlebotomists to your door. The draw takes under 10 minutes.

Temperature-Controlled Transport

Your sample is sealed and transported via cold-chain courier to our CLIA lab — maintaining integrity for the most accurate results.

Results Delivered to Your Phone

A secure digital report lands in your inbox within 24 hours. No chasing down results — everything is clear and explained.

Our Technology

Powered by Fusion-detect™ AI

Fusion-detect™ is our proprietary genomic sequencing and AI analysis platform. It detects chromosomal fusion events — a hallmark of early-stage HCC — that are completely missed by conventional blood markers like AFP.

The platform has gone through four major AI training generations, each time dramatically improving detection accuracy. Here’s how AI transformed liver cancer detection:

2018 — Foundation

Fusion Gene Discovery

Researchers identified 14 HCC-specific fusion gene events in circulating tumor DNA that appear up to 18 months before imaging-detectable tumors.

2020 — Breakthrough

Fusion Gene Discovery

Initial ML classifier trained on 8,000 samples. Already outperformed AFP testing — but we knew we could go further.

2022 — Scale

Deep Learning on 50K Samples: 92.1%

A transformer-based neural network trained on 50,000+ annotated patient samples across 12 ethnic backgrounds for bias-free results.

2024 — Present

Fusion-detect™ v4: 96.7% Accuracy

Real-time ensemble AI with multi-biomarker fusion scoring, continuous learning pipeline, and <3% false positive rate. CLIA-certified and peer-review validated.

AI Accuracy Progression

How AI Transformed Our Detection Rate

v1 Model (2020) — 8K samples

78%

v2 Model (2021) — 20K samples

86.3%

v3 Model (2022) — 50K samples

92.1%

v4 Fusion-detect™ (2024 — Current)

96.7%

vs. Current Clinical Standard

Standard AFP Test

~52%

✦ 96.7% accuracy confirmed across 3 independent clinical validation cohorts. Results submitted for peer-reviewed publication.

The Growing Crisis

Liver Cancer Cases Are Rising Every Year

WHO and SEER data confirm liver cancer (HCC) is one of the world’s fastest-growing cancers. Without early detection tools, this trend means more late-stage diagnoses and preventable deaths.

Global & US Liver Cancer (HCC) Incidence — 2015 to 2023

Source: WHO Global Cancer Observatory (GLOBOCAN), NCI SEER Program 2023
The trajectory is clear: liver cancer is rising steadily. Early detection via blood-based screening is the only scalable intervention that can reverse the mortality curve without requiring massive infrastructure investment.

Latest Insights

From the MoleculeDx Journal

The WHO Data on Liver Cancer No One Is Talking About

The WHO Data on Liver Cancer No One Is Talking About

Global liver cancer incidence has risen 75% over the past 20 years. We break down the WHO GLOBOCAN numbers — and what they mean for high-risk patients in the US right now.

Why Your Liver Cancer Screening Probably Isn’t Enough

Why Your Liver Cancer Screening Probably Isn’t Enough

If you have hepatitis, cirrhosis, or NAFLD, your doctor may be relying on ultrasound and AFP — tools that miss over 40% of early-stage HCC. Here’s what the evidence shows.

How AI Is Closing the Early Detection Gap in Liver Cancer

How AI Is Closing the Early Detection Gap in Liver Cancer

Machine learning models trained on fusion gene biomarkers are outperforming 40 years of conventional AFP testing — and changing what’s possible in oncology screening.

Our Partners

A Trusted Network Behind Every Test

We’ve partnered with the best in US phlebotomy, clinical medicine, and health insurance to make testing seamless from booking to results.

P

Portamedic

One of America’s largest mobile health services networks — certified phlebotomists serving all 50 states, available 7 days a week for at-home blood draws.

T

Travalab

Travalab’s mobile laboratory specialists provide concierge-level phlebotomy services, ensuring the highest sample quality and patient comfort from first contact.

UPMC

UPMC (Exclusive Clinical Partner)

University of Pittsburgh Medical Center — our exclusive clinical partner. UPMC patients and the public can walk in for testing at any UPMC facility.

Insurance Partners

Accepted by Major US Insurers

Not sure if you’re covered? Our patient support team will verify your insurance coverage for free before you book. Call us or check online at booking.moleculedx.com.

Exclusive Partnership

Testing Available at Every UPMC Location

Through our exclusive partnership with University of Pittsburgh Medical Center, you can walk into any UPMC facility today — no prior appointment required for testing referral.

Walk-In Access

No appointment needed at UPMC sites

Physician Oversight

UPMC oncologists review flagged results

Research-Backed

Supported by UPMC clinical research program

EHR Integration

Results flow directly into your UPMC medical record

Your Liver Health Can't Wait.

A simple blood test could be the most important thing you do this year. Book online in 2 minutes and have a phlebotomist at your door within 48 hours.