Patient guide | Blood-based HCC detection
Can Liver Cancer Be Detected by a Blood Test?
What AFP, AFP-L3, DNA methylation and fusion-transcript research can—and cannot—tell us about liver cancer.
Read article →MoleculeDx
From the MoleculeDx Journal
Patient-friendly perspectives on HCC surveillance, biomarkers and molecular research.
Patient guide | Liver cancer screening
Test for Liver Cancer: What to Expect Before, During, and After Screening
Learn what to expect before, during and after screening, how results are interpreted, and what clinical validation reports about Fusion-detect™.
Read article →Blood test for liver cancer
Blood Test for Liver Cancer: How It Works and What Results Mean
Who needs HCC surveillance, how fusion-transcript testing works, what positive or negative reports mean, and what small-tumor studies show.
Read article →U.S. liver cancer statistics
Liver Cancer in the USA: 2026 Statistics Every American Should Know
Verified ACS projections, SEER survival statistics by stage, risk factors and HCC surveillance guidance.
Read article →Screening guidelines | 2026
What Is HCC Liver Cancer? 2026 Screening Guidelines & Early Detection
Who needs surveillance, why six-month ultrasound and AFP matter, and how hepatitis B changes individual risk.
Read article →Ultrasound vs. blood tests
HCC Blood Test vs. Ultrasound: What Is the Difference?
How ultrasound, AFP and emerging molecular tests differ—and why standard HCC surveillance uses imaging with AFP.
Read article →Understanding AFP
Why Can Liver Cancer Occur With a Normal AFP?
AFP is a useful biomarker, but some patients with HCC have AFP levels within the normal range. Different molecular signals can provide additional biological information.
Read article →Early detection
Why Early Detection Matters in Liver Cancer
Because early-stage HCC may have few symptoms, appropriate surveillance can help identify concerning changes before symptoms occur.
Read article →Risk and surveillance
Who Should Consider an HCC Screening Test?
Cirrhosis, selected chronic HBV conditions, and other liver-disease risk factors shape the need for ongoing HCC surveillance.
Read article →Molecular biology
Why Molecular Testing for Liver Cancer Matters
Molecular tests investigate cancer-associated DNA and RNA signals that can complement conventional clinical evaluation.
Read article →Longitudinal monitoring
5 Benefits of Regular Liver Cancer Surveillance
Repeated monitoring provides an opportunity to evaluate trends rather than relying on a single snapshot.
Read article →Biomarkers
Liver Cancer Blood Markers: What Do They Tell Us?
AFP, liver function measurements, and circulating fusion transcripts examine very different aspects of liver biology.
Read article →Patient experience
What to Expect From a Liver Cancer Blood Test
An overview of ordering, blood collection, laboratory analysis, reporting and follow-up.
Read article →Risk factors
Liver Cancer Screening: Hepatitis, Cirrhosis and Family History
Chronic hepatitis B, hepatitis C, cirrhosis, and family history influence HCC risk in different ways.
Read article →Research
How Fusion Transcripts Are Changing Blood-Based Liver Cancer Research
Genomic fusion events can yield RNA transcripts that are investigated as cancer-associated serum signals.
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